Researchers Discover Enzyme Triggers Prostate Cancer
The researchers now are developing compounds that may limit the growth and spread of prostate cancer cells.
Researchers at Mayo Clinic, Florida succeeded in identifying enzymes associated with aggressive prostate cancer.
Now they have developed compounds that can limit the growth and spread of cancer cells.
The study, published in the journal Molecular Cancer Research is the first to study the relationship of enzymes P28RSS3 with prostate cancer.
“These molecules are able to swallow the other molecules. Our data suggest that the activity of PRSS3 provide changes to the environment surrounding the prostate cancer cells. Possibility that the enzyme freeing cancer cells from the surrounding tissue and make the cancer cells more aggressive,” says researcher , Evette Radisky.
The findings obtained through observation of data from numerous clinical studies. Previous research team found an association between protease molecules and early stage breast cancer. Then they wanted to see the effect on other types of cancer.
“We were able to determine the relationship between activity PRSS3 and aggressive prostate cancer,” said Radisky.
“We found that increased activity of cells PRSS3 trigger malignant prostate cancer. However, we give a compound able to block it.”